Reciprocal Space Station

open-source structural biology powered by AI

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What we do

Open science for the next generation of structural biology

RSS is a consortium developing an open-source ecosystem for methods spanning X-ray crystallography, cryo-EM, and the AI that increasingly connects structure to function. We're an open community that welcomes contributions from academics, industry, and non-profits across the world of structural biology.

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1/🛸 reciprocalspaceship

Tools for exploring reciprocal space. This package provides a crystallographically-aware extension of pandas and othe...

🎲 careless

Applying variational inference to the scaling and merging of crystallographic data.

🗺️ matchmaps

Make difference maps between near-isomorphous or non-isomorphous datasets.

🌈 laue-dials

Extending DIALS for polychromatic “pink beam” data collected at Laue X-ray sources.

🧮 SFCalculator

A differentiable pipeline connecting the protein atomic models and experimental structure factors, featuring a differ...

☄️ METEOR

Map Enhancement Tools for Ephemeral Occupancy Refinement is a tool for computing crystallographic difference maps.

🚀 ROCKET

Refining Openfold predictions with Crystallographic/Cryo-EM LiKElihood Targets (ROCKET) is a tool that uses neural ne...

🛠️ Development Zone

More RSS packages under active development — use at your own risk!

Community Forum

Ask questions, share ideas, and discuss crystallographic data analysis with the RS Station community on our open-source Discourse forum.

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